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Gene Rep ; 21: 100910, 2020 Dec.
Article in English | MEDLINE | ID: covidwho-837457

ABSTRACT

We decided to examine suspected samples of pneumonia outbreak caused by the new coronavirus SARS-CoV-2 and provide information about the mortality rate due to this infection in different age groups in Iran. In this descriptive-cross-sectional study, a total of 784 samples of naso/oropharyngeal swabs of suspected patients with COVID-19 symptoms who had referred to Imam Khomeini, Shahid Fayaz-Bakhsh and Modarres hospitals in Tehran from February 24, 2020 to March 24, 2020 were examined by RT-PCR method. The highest incidence of the disease was within the age group of 50-59 years, while the lowest rate was in the 0-9 years age group. The highest rate of positive samples in terms of COVID-19 among suspected individuals was for patients >80 years of age (89%) and the highest mortality rate was in the age range of 70-79 years (31%) and >80 years (30), respectively. In terms of recovery, the highest rate was in the 30-39 years age group (65.2%). Statistical analysis showed that mortality significantly increased in the age group of >60 years old and in fact, mortality was significantly associated with older ages. According to the results of the current study, the prevalence of COVID-19 in lower age (0-9 years old) is lower and mortality rate is higher in older ages as significant increase in mortality was observed in those aged >60 years old. However, further epidemiological studies on a larger study population in different regions of Iran are needed to explain the prevalence, clinical features, and course of the disease.

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